PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 29, 2026Proceedings of the National Academy of Sciences

Plants tolerate substantial rates of plastid mistranslation via regulated proteostasis

View Full Paper
Ask AI
Bookmark
Share

Authors

BBB BrandtSSSebastian SchwartzSSSerena Schwenkert

Discussion

Loading...

Member takes

Overview

Randomized trial investigates plastid mistranslation effects in plants, indicating unique compensation mechanisms.

Key Points

  • This research aims to understand how plant cells tolerate mistranslation of proteins in plastids and mitochondria.
  • Analyzed Arabidopsis mutants with altered GatCAB activity to assess mistranslation rates.
  • Conducted proteomics analyses to compare misincorporation rates in organellar-expressed protein complexes.
  • Investigated temperature stress effects on Gln-to-Glu misincorporation in wild-type and hypermistranslating mutants.
  • In mutants, high plastid and low mitochondrial Gln-to-Glu misincorporation rates were observed.
  • Only modest changes in protein abundance were noted in plastids and none in mitochondria.
  • Wild-type plants under temperature stress exhibited altered Gln-to-Glu misincorporation rates.

Cite This Study

Brandt et al. (2026) studied this question.

synapsesocial.com/papers/6a192f1bfab5b468c4418760https://doi.org/10.1073/pnas.2537357123
View Full Paper
Ask AI
Bookmark
Share