Green Synthesis and Characterization of Silver Nanoparticles Using Asparagus officinalis and their Anti-Inflammatory and Antioxidant Activities: In Silico, In Vitro, and In Vivo Studies

Key Points

• The aim is to explore the antioxidant and anti-inflammatory activities of silver nanoparticles synthesized from Asparagus officinalis.
• Utilized ethanolic root extract from Asparagus officinalis for synthesizing silver nanoparticles (AgNPs).
• Conducted in silico, in vitro, and in vivo evaluations of the AgNPs' properties.
• Characterized the AgNPs for their effectiveness in combating oxidative stress and inflammation.
• AgNPs demonstrated significant antioxidant activity, evidenced by a reduction in oxidative markers.
• The anti-inflammatory effects were validated through multiple assays, indicating effective therapeutic potential.
• Highlights a foundation for herbal-based nanomedicine for managing inflammation-related disorders.