Key result
Lipid metabolism disorders are linked to depression and suicidal behavior despite a complex relationship.
Why the study?
Mental disorders, rising suicide rates, and the search for biological markers like lipid metabolism indicators motivated this analysis for early detection and prevention.
Is there an association between lipid profile and depressive disorders, including suicidal behavior?
Is there an association between lipid profile and depressive disorders, including suicidal behavior?
Answers are grounded in this paper and cite their sources.
This review highlights a complex and controversial association between lipid metabolism disorders and depressive disorders, including suicidal behavior.
A BSTRACT Introduction: The problem of mental disorders and the increase in suicides, as well as the search for biological markers, such as lipid metabolism indicators, are of considerable interest for early detection and prevention. Objective: To analyze the current scientific data on the relationship between lipid profile and depressive disorders, including suicidal behavior. Search Strategy: The literature review covered 28 years from 1996 to 2024 and included the following databases: PubMed, Scopus, and Web of Science Core Collection. Inclusion criteria: analysis of descriptive, analytical, clinical studies, and systematic reviews, in English and Russian languages, regardless of country and nationality. Results and Conclusions: The literature review revealed an association between lipid metabolism disorders and mental disorders, including depression and suicidal behavior, which is supported by current data but remains controversial due to the complex, multifactorial nature of this interaction.
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Abenova et al. (2025) conducted a review in Depressive disorders and suicidal behavior. Lipid profile was evaluated on Association between lipid profile and depressive disorders or suicidal behavior. Lipid metabolism disorders are associated with mental disorders, including depression and suicidal behavior, although the relationship remains controversial due to its complex, multifactorial nature.
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