Key result
Hypertension increased the lifetime risk of overall cardiovascular disease at 30 years of age to 63.3% compared with 46.1% for normal blood pressure, and led to developing the disease 5.0 years earlier.
Why the study?
Does prophylactic oral tocopherol prevent CI-AKI in patients with CKD undergoing coronary procedures?
Cohort (n=1,250,000)
Yes
Does prophylactic oral tocopherol prevent CI-AKI in patients with CKD undergoing coronary procedures?
Absolute Event Rate: 63.3% vs 46.1%
Prophylactic oral α- or γ-tocopherol combined with saline infusion significantly reduces the incidence of contrast-induced acute kidney injury in CKD patients undergoing coronary procedures.
Hypertension markedly raises lifetime CVD risk from age 30; leaves open whether early intervention alters trajectories in prospective studies.
P for interaction = 0.97. The rate of in-hospital dialysis (4.1% versus 0.7%; P = 0.056) were higher in the control group. Further studies are needed to compare LVEDP-guided versus RenalGuard system-guided hydration regimens.
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Sujoy Banik (2014) conducted a cohort in Cardiovascular disease (n=1,250,000). Hypertension vs. Normal blood pressure was evaluated on Lifetime risk of overall cardiovascular disease at 30 years of age. Hypertension increased the lifetime risk of overall cardiovascular disease at 30 years of age to 63.3% compared with 46.1% for normal blood pressure, and led to developing the disease 5.0 years earlier.
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