What does this research mean for the field?

The canine left ventricle contracts in an eccentric manner and relaxes in a concentric fashion, and the magnitude of change in its cross-sectional area during ejection can serve as an index of stroke volume and contraction efficiency. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To characterize instantaneous changes in left ventricular geometry, including base-to-apex length and cross-sectional area, across distinct phases of the cardiac cycle.

January 1, 1961Circulation Research

Instantaneous Dimensional Changes of the Left Ventricle in Dogs

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To characterize instantaneous changes in left ventricular geometry, including base-to-apex length and cross-sectional area, across distinct phases of the cardiac cycle.
Monitored instantaneous changes in left ventricular base-to-apex length, cross-sectional area, and circumference in awake intact dogs and open-chest canine models.
Evaluated dynamic dimensional changes across isovolumic contraction, ejection, isovolumic relaxation, rapid filling, diastasis, and atrial systole.
Isovolumic contraction involved base-to-apex shortening with increased cross-sectional area, showing total shortening approximately one-fourth of that observed in open-chest dogs.
Ventricular ejection demonstrated minimal base-to-apex length alterations alongside progressive cross-sectional area reduction that correlates with stroke volume.
Left ventricular dynamics revealed an eccentric pattern of contraction during systole and a concentric pattern during diastolic relaxation.

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Implication

Intact-dog patterns differ markedly from open-chest models; leaves open translational relevance to human LV mechanics.

Cite This Study

Edward W. Hawthorne (1961) studied this question.

synapsesocial.com/papers/6a19324ca0353395e957ff0e https://doi.org/10.1161/01.res.9.1.110

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Instantaneous Dimensional Changes of the Left Ventricle in Dogs

Key Points

Discussion

Implication

Cite This Study

Instantaneous Dimensional Changes of the Left Ventricle in Dogs

Key Points

Discussion

Implication

Cite This Study

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