Key result
High compliance with ACSM exercise guidelines improves total cholesterol, HDL, and BMI after PCI.
Why the study?
The impact of exercise dosages based on American College of Sports Medicine (ACSM) recommendations on lipid metabolism in patients after PCI remains unclear.
Does high compliance with ACSM-recommended exercise dosages improve lipid metabolism and BMI in patients after PCI?
Meta-Analysis (n=859)
Does high compliance with ACSM-recommended exercise dosages improve lipid metabolism and BMI in patients after PCI?
High compliance with ACSM-recommended exercise dosages significantly improves total cholesterol, HDL, and BMI in post-PCI patients, but provides no additional advantage for triglycerides or LDL levels.
Answers are grounded in this paper and cite their sources.
High compliance with ACSM exercise improves TC, HDL, and BMI post-PCI; extends evidence for dosing in cardiac rehabilitation.
Background The impact of exercise dosages based on American College of Sports Medicine(ACSM) recommendations on lipid metabolism in patients after PCI remains unclear. This study conducted a meta-analysis of reported exercise dosages from the literature to address this knowledge gap. Methods A comprehensive search of databases was conducted to identify eligible randomized controlled studies of exercise interventions in patients after PCI, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Based on the recommended exercise dosages from ACSM for patients with coronary heart disease, exercise doses in the literature that met the inclusion criteria were categorized into groups that were highly compliant with ACSM recommendations and those with low or uncertain ACSM recommendations. The topic was the effect of exercise dose on lipid metabolism in post-PCI patients. This was assessed using standardized mean difference (SMD) and 95% confidence intervals (95% CI) for changes in triglycerides, total cholesterol, LDL, and HDL. Results This systematic review included 10 randomized controlled studies. The subgroup analysis revealed statistically significant differences in the high compliance with ACSM recommendations group for triglycerides [SMD=-0.33 (95% CI -0.62, -0.05)], total cholesterol [SMD=-0.55 (95% CI -0.97, -0.13)], low-density lipoprotein [SMD=-0.31 (95% CI -0.49, -0.13)], high-density lipoprotein [SMD = 0.23 (95% CI 0.01, 0.46)], and body mass index [SMD=-0.52 (95% CI -0.87, -0.17)]. Compared to the low or uncertain compliance with ACSM recommendations group, the high compliance group exhibited significant differences in improving TC levels (-0.55 (H) vs. -0.46 (L) ), HDL levels (0.23 (H) vs. 0.22 (L) ), and BMI (-0.52 (H) vs. -0.34 (L) ). Conclusions This study supports that high compliance with ACSM-recommended exercise dosages has significant impacts on improving TC levels, HDL levels, and BMI. However, no advantage was observed for TG or LDL levels.
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Wen et al. (2024) conducted a meta-analysis in Patients after percutaneous coronary intervention (PCI) (n=859). Exercise dosages with high compliance to ACSM recommendations vs. Low or uncertain compliance with ACSM recommendations or no exercise was evaluated on Total cholesterol (high compliance group) (SMD -0.55, 95% CI -0.97, -0.13, p=0.01). High compliance with ACSM-recommended exercise dosages significantly improved total cholesterol (SMD -0.55), high-density lipoprotein (SMD 0.23), and body mass index in patients after PCI.
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