Key result
Polyethylene-terephthalate graft aortitis caused by Aspergillus niger is a rare condition requiring early diagnosis with TEE and prompt surgical and antifungal therapy to reduce high mortality.
Why the study?
Fungal endocarditis/aortitis is an emerging entity with poor prognosis, and polyethylene-terephthalate graft aortitis caused by Aspergillus niger had not been previously reported.
Case Report (n=1)
Highlights the first case of A. niger PETE graft aortitis and emphasizes early TEE, surgery, and antifungal therapy for management.
Answers are grounded in this paper and cite their sources.
Alerts to fungal etiologies in graft infections; hypothesis-generating for TEE-guided management of rare Aspergillus aortitis.
Fungal endocarditis/aortitis is an uncommon yet emerging entity accounting for 2% to 4% of all cases of infective endocarditis and continues to be associated with a poor prognosis. We present the first case of polyethylene-terephthalate (PETE) graft aortitis caused by A. niger, a rare fungal agent. Early diagnosis with frequent transoesophageal echocardiography (TEE) and a prompt surgical intervention coupled with optimal antifungal therapy are still the only option to reduce the exceedingly high mortality and morbidity.
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Marro et al. (2020) conducted a case report in Polyethylene-terephthalate (PETE) graft aortitis caused by Aspergillus niger (n=1). Surgical intervention and antifungal therapy was evaluated. Polyethylene-terephthalate graft aortitis caused by Aspergillus niger is a rare condition requiring early diagnosis with TEE and prompt surgical and antifungal therapy to reduce high mortality.
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