Serum 25-Hydroxyvitamin D Concentration and Subsequent Risk of Type 2 Diabetes

t has been suggested that vitamin D reduces the risk of type 2 diabetes. The finding that vitamin D deficiency is associated with impaired -cell function and insulin resistance in animals (1,2) and humans (3,4) is in line with that hypothesis. In the only cohort study publ i s h e d , t h e i n t a k e o f v i t a m i n D supplements was inversely associated with the development of type 2 diabetes (5). Since vitamin D intake covers only a part of the total vitamin D available, the purpose of this study was to evaluate the prediction of serum 25-hydroxyvitamin D (25OHD) on subsequent type 2 diabetes incidence.