Key result
ICD or CRT-D implantation is linked to significant improvements in heart-focused anxiety and quality of life.
Why the study?
The study investigated heart-focused anxiety, general anxiety, depression, and quality of life in patients with heart failure before and up to 2 years after ICD or CRT-D implantation.
Does ICD or CRT-D implantation improve heart-focused anxiety, general anxiety, depression, and quality of life in patients with chronic heart failure?
Cohort (n=132)
No
Does ICD or CRT-D implantation improve heart-focused anxiety, general anxiety, depression, and quality of life in patients with chronic heart failure?
Effect estimate: ηp2 = 0.07
p-value: p=<0.001
ICD and CRT-D implantation in heart failure patients is associated with improvements in general anxiety, heart-focused anxiety, and quality of life, though depression and avoidance of physical activity remain unchanged, highlighting the need for targeted psychological counseling.
May benefit anxiety and QoL in HF device recipients; leaves open depression impact and needs prospective validation.
AIMS: The Anxiety-CHF (Anxiety in patients with Chronic Heart Failure) study investigated heart-focused anxiety (HFA, with the dimensions fear, attention, and avoidance of physical activity), general anxiety, depression, and quality of life (QoL) in patients with heart failure. Psychological measures were assessed before and up to 2 years after the implantation of an implantable cardioverter defibrillator (ICD) with or without cardiac resynchronization therapy defibrillator (CRT-D). METHODS AND RESULTS: One hundred thirty-two patients were enrolled in this monocentric prospective study (44/88 CRT-D/ICD, mean age 61 ± 14 years, mean left ventricular ejection fraction 31 ± 9%, and 29% women). Psychological assessment was performed before device implantation as well as after 5, 12, and 24 months. After device implantation, mean total HFA, HFA-fear, HFA-attention, general anxiety, and QoL improved significantly. Depression and HFA-related avoidance of physical activity did not change. CRT-D patients compared with ICD recipients and women compared with men reported worse QoL at baseline. Younger patients (<median of 63 years) had higher levels of general anxiety and lower levels of HFA-avoidance at baseline than older patients. After 24 months, groups no longer differed from each other on these scores. Patients with a history of shock or anti-tachycardia pacing (shock/ATP; N = 19) reported no improvements in psychological measures and had significantly higher total HFA and HFA-avoidance levels after 2 years than participants without shock/ATP. CONCLUSIONS: Anxiety and QoL improved after device implantation, and depression and HFA-avoidance remained unchanged. HFA may be more pronounced after shock/ATP. Psychological counselling in these patients to reduce HFA and increase physical activity should be considered.
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Kindermann et al. (2021) conducted a cohort in Chronic Heart Failure (n=132). ICD or CRT-D implantation vs. Baseline (pre-implantation) was evaluated on Change in mean total heart-focused anxiety (HFA) score (ηp2 = 0.07, p=<0.001). ICD or CRT-D implantation was associated with significant improvements in total heart-focused anxiety (P<0.001), general anxiety, and quality of life, while depression and HFA-avoidance remained unchanged.
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