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A preliminary evaluation of the bone-localizing properties of 99mTc-pyrophosphate demonstrates favorable skeletal concentration, rapid blood and renal clearance, and ease of chemical reproducibility. The authors report the results of bone imaging with 99mTc-pyrophosphate for the detection of osseous metastases in 30 patients with known or suspected primary carcinoma.
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Fletcher et al. (1973) studied this question.
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