Key result
Advanced interatrial block with biphasic inferior P-waves is linked to AF, stroke, dementia, and premature death.
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Interatrial block, particularly advanced interatrial block, has distinct ECG features and serves as a significant risk factor for adverse clinical outcomes including atrial fibrillation and stroke.
Interatrial blocks like other types of block may be of first degree or partial second degree, also named transient atrial block or atrial aberrancy, and third degree or advanced. In first degree, partial interatrial block (P-IAB), the electrical impulse is conducted to the left atrium, through the Bachmann’s region, but with delay. The ECG shows a P-wave ≥ 120 ms. In third-degree, advanced interatrial block (A-IAB), the electrical impulse is blocked in the upper part of the interatrial septum (Bachmann region); the breakthrough to LA has to be performed retrogradely from the AV junction zone. This explains the p ± in leads II, III and aVF. In typical cases of A-IAB, the P-wave morphology is biphasic (±) in leads II, III and aVF, because the left atrium is activated retrogradely and, therefore, the last part of the atrial activation falls in the negative hemifield of leads II, III and aVF. Recently, some atypical cases of A-IAB have been described. The presence of A-IAB is a risk factor for atrial fibrillation, stroke, dementia, and premature death.
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Luna et al. (2021) conducted a review in Interatrial block. Advanced interatrial block, characterized by biphasic P-waves in inferior leads, is a recognized risk factor for atrial fibrillation, stroke, dementia, and premature death.
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