Why the study?
The study investigated the prognostic value of dynamic changes of P-wave terminal force in lead V1 (PtfV1) on ECG for long-term major adverse cardiovascular events in patients with NSTE-ACS.
Do dynamic changes of P-wave terminal force in lead V1 (PtfV1) predict major adverse cardiovascular events in patients with non-ST-segment elevation acute coronary syndrome?
Observational (n=905)
No
Do dynamic changes of P-wave terminal force in lead V1 (PtfV1) predict major adverse cardiovascular events in patients with non-ST-segment elevation acute coronary syndrome?
Answers are grounded in this paper and cite their sources.
The persistence of a positive P-wave terminal force in lead V1 or its conversion from negative to positive during hospitalization is an independent predictor of long-term major adverse cardiovascular events in patients with NSTE-ACS.
Background The purpose of this study was to investigate the prognostic value of dynamic changes of P‐wave terminal force in lead V 1 (PtfV 1 ) at electrocardiogram (ECG) in patients with non–ST‐segment elevation acute coronary syndrome (NSTE‐ACS) during the long‐term major adverse cardiovascular events (MACEs) of patients. Methods According to the PtfV 1 value, the patients were divided into four groups: PtfV 1 (−)/PtfV 1 (−), PtfV 1 (−)/PtfV 1 (+), PtfV 1 (+)/PtfV 1 (−), and PtfV 1 (+)/PtfV 1 (+). Results The highest incidence of MACEs was the PtfV 1 (−)/(+) group with 24 patients (24.7%). The lowest incidence was the PtfV 1 (−)/(−) group with 28 patients (4.9%). Compared with the PtfV 1 (−)/(−) group, the risk for the occurrence of MACEs in the PtfV 1 (−)/(+)group was significantly increased (24.7% vs 4.9%, P = .000). Similarly, the risk in the PtfV 1 (+)/(+) group was also increased (10.1% vs 4.9%, P = .000). Conclusion The persistence of PtfV 1 (+) and conversion of PtfV 1 /(−) to PtfV 1 /(+) at discharge significantly increased the incidence of MACEs.
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Lin et al. (2020) conducted an observational in Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) (n=905). Conversion of PtfV1(-) to PtfV1(+) at discharge vs. Persistent PtfV1(-) was evaluated on Composite of major adverse cardiovascular events (MACEs) (HR 3.548, 95% CI 2.024-6.219, p=<0.001).
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