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Narrative review outlines advances in targeted therapies for rheumatoid arthritis, suggesting improved prevention of irreversible joint damage.
Rheumatoid arthritis affects about 1 percent of the U.S. population and can cause irreversible joint deformities and functional impairment. Although the cause of this autoimmune disease remains obscure, greater understanding of its underlying mechanisms has facilitated the development of new drugs and revolutionized treatment.
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Olsen et al. (2004) studied this question.
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