June 11, 2019Current Vascular Pharmacology
Gender-specific, Lifestyle-related Factors and 10-year Cardiovascular Disease Risk; the ATTICA and GREECS Cohort Studies
Why the study?
Lifestyle drives CVD onset and progression and lifestyle patterns depend on gender-related attitudes, but the gender-specific association of lifestyle factors with 10-year first and recurrent CVD events needed evaluation.
Do lifestyle-related factors (Mediterranean diet, physical activity, smoking) predict 10-year first and recurrent CVD events differently in men and women?
Population
3,042 subjects free-of-CVD and 2,172 subjects with ACS
Comparison
Mediterranean diet adherence, physical activity levels, and smoking status compared across men and women
Design
Two prospective cohort studies
Follow-up
10-year
Authors
Discussion
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Member takes
Implication
Gender-specific lifestyle associations with first CVD events are hypothesis-generating; prospective trials needed before informing tailored prevention.
Structured PICO
Do lifestyle-related factors (Mediterranean diet, physical activity, smoking) predict 10-year first and recurrent CVD events differently in men and women?
P
Population
5,214 subjects from two prospective studies: ATTICA (n=3,042 subjects free-of-CVD) and GREECS (n=2,172 subjects with Acute Coronary Syndrome (ACS)).
I
Intervention
Lifestyle-related factors: adherence to Mediterranean diet (MedDietScore <27/≥27), Physical Activity (sedentary/physically active), and smoking (current/never).
O
Outcome
10-year first (ATTICA) and recurrent (GREECS) CVD eventshard clinical
Gender-specific differences exist in the impact of lifestyle factors on the 10-year risk of first and recurrent cardiovascular events, highlighting the need for tailored prevention strategies.
Cite This Study
Kouvari et al. (2019) studied this question.