Why the study?
The impact of hypertension duration and time of onset on metabolic syndrome and other CV risk factors in perimenopausal women had not been studied.
Does hypertension duration and age of onset affect the expression of metabolic syndrome and cardiovascular risk factors in perimenopausal women?
Does hypertension duration and age of onset affect the expression of metabolic syndrome and cardiovascular risk factors in perimenopausal women?
Hypertension onset around the time of menopause is associated with abdominal obesity and an increased accumulation of cardiovascular risk factors, including metabolic syndrome.
Answers are grounded in this paper and cite their sources.
Longer hypertension duration associates with metabolic syndrome in perimenopausal women; leaves open whether menopause-onset hypertension drives risk accumulation.
Background . The impact of hypertension duration and the time of onset on the expression of metabolic syndrome (MS) and other CV risk factors, in perimenopausal women, have not been studied so far. Methods. A total of 202 women, old 47–59 years, and diagnosed with hypertension, were recruited from primary care practices in eastern Croatia. The categories of hypertension duration were defined as <5, 5–10, and >10 years. Data were analyzed by standard statistical procedures. Results . The proportion of women with MS increases in parallel with hypertension duration ( p = 0.025). Among the examined CV risk factors, significant increase in parallel with hypertension duration was found for body mass index ( p = 0.007) and triglycerides ( p = 0.07). The highest proportion of women with diabetes duration of less than 5 years, indicating recent diabetes onset, was found in the category of hypertension duration of less than 5 years, corresponding with the onset of hypertension in the time around menopause ( p = 0.003). The strongest linear correlations with BMI and waist circumference were found for total serum cholesterol ( r = 0.355 and 0.499, respectively). Conclusion . Hypertension onset at the time around menopause appears together with abdominal obesity and may be a driving force for CV risk factor accumulation in postmenopausal women.
No takes yet. Share an insight, caveat, or question.
Majnarić et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: