This case highlights that chronic HTLV-I infection can present with non-neoplastic inflammation manifesting as diffuse panbronchiolitis-like lesions, uveitis, and ulcerative colitis.
Answers are grounded in this paper and cite their sources.
May warrant HTLV-I testing in unexplained uveitis, colitis, and bronchiolitis; single case leaves open causal confirmation.
A 45-year-old male was referred due to prolonged productive cough. Despite the fact that bronchoalveolar lavage fluid suggested lymphocytic and neutrophilic alveolitis, the histologic diagnosis of his biopsied lung was diffuse panbronchiolitis-like lesion with infiltration of lymphocytes and plasma cells into respiratory bronchioles but few foamy cells. Serologic examination revealed that he was a carrier of human T-cell lymphotropic virus type I (HTLV-I). Together with uveitis and ulcerative colitis in his past history, the persistent respiratory symptoms of this patient can be attributed to non-neoplastic inflammation due to the chronic HTLV-I infection.
No takes yet. Share an insight, caveat, or question.
Kikuchi et al. (1996) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: