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This review aims to provide an overview of the technologies which make the nematode Caenorhabditis elegans an attractive genetic model system. We describe transgenesis techniques and forward and reverse genetic approaches to isolate mutants and clone genes. In addition, we discuss the new possibilities offered by genome engineering strategies and next‐generation genome analysis tools. WIREs Dev Biol 2012, 1:114–137. doi: 10.1002/wdev.1 This article is categorized under: Technologies > Perturbing Genes and Generating Modified Animals
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Boulin et al. (2011) studied this question.
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