Why the study?
The study was conducted to evaluate serum biomarkers implicated in platelet-endothelium interaction and the efficacy of antiplatelet therapy in patients with aortic stenosis and CAD.
Does the presence of aortic stenosis affect platelet-related biomarkers and the efficacy of aspirin therapy in patients with coronary artery disease?
Does the presence of aortic stenosis affect platelet-related biomarkers and the efficacy of aspirin therapy in patients with coronary artery disease?
In patients with coronary artery disease, the coexistence of aortic stenosis is associated with elevated biomarkers of endothelial damage and platelet activation, but does not impair the efficacy of aspirin therapy.
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Aortic stenosis was associated with higher TM/PF4 but unchanged aggregation; leaves open any impact on antiplatelet efficacy in CAD.
Bańka et al. (2025) studied this question.
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