What does this research mean for the field?

Both the TIMI and Mori grading systems independently predict clinical outcomes after intra-arterial thrombolysis for stroke, but the Mori classification provides more refined prognostic information in cases of partial recanalisation. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 16, 2005Journal of Neurology Neurosurgery & PsychiatryOpen Access

Recanalisation of middle cerebral artery occlusion after intra-arterial thrombolysis: different recanalisation grading systems and clinical functional outcome

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Why the study?

Does the Mori grading system provide more refined prognostic information than the TIMI grading system for clinical outcome in stroke patients treated with intra-arterial thrombolysis?

Population

147 patients with M1 or M2 segment occlusion of the middle cerebral artery treated with intra-arterial…

Comparison

Mori grading system for arterial recanalisation vs TIMI grading system for arterial recanalisation

Design

Cohort

Follow-up

3 months

Authors

MAMarcel ArnoldGoethe University Frankfurt

Discussion

Member takes

Implication

Mori grading may refine prognosis in partial recanalization after intra-arterial thrombolysis; leaves open whether it should supplant TIMI in practice or trials.

Structured PICO

Does the Mori grading system provide more refined prognostic information than the TIMI grading system for clinical outcome in stroke patients treated with intra-arterial thrombolysis?

Population

147 patients with M1 or M2 segment occlusion of the middle cerebral artery treated with intra-arterial thrombolysis (IAT), median NIHSS score on admission 15, mean time from symptom onset to IAT 242 minutes.

Intervention

Mori grading system for arterial recanalisation

Comparator

TIMI grading system for arterial recanalisation

Outcome

Clinical functional outcome at 3 months (favourable defined as modified Rankin scale score (mRS) ≤ 2)hard clinical

The Mori grading system provides more refined prognostic information than the TIMI grading system for stroke patients with partial recanalisation after intra-arterial thrombolysis.

Cite This Study

Marcel Arnold (2005) studied this question.

synapsesocial.com/papers/6a196c6cf2eb401dc7891148 https://doi.org/10.1136/jnnp.2004.055160

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Implication

Mori grading may refine prognosis in partial recanalization after intra-arterial thrombolysis; leaves open whether it should supplant TIMI in practice or trials.

Recanalisation of middle cerebral artery occlusion after intra-arterial thrombolysis: different recanalisation grading systems and clinical functional outcome

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Recanalisation of middle cerebral artery occlusion after intra-arterial thrombolysis: different recanalisation grading systems and clinical functional outcome

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider