Clinical Significance of Adjusting the Estimated Glomerular Filtration Rate by an Individual’s Body Surface Area from the Perspective of the Cardio-ankle Vascular Index: A Cross-sectional Study

Figures

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  Fig.1. Relationship of two kidney function parameters with aging in male and female participants. Bar charts of the eGFR or the BSA-adjusted eGFR stratified by age in (A) males and (B) females are presented. p＜0.001 comparing the BSA-adjusted eGFR with the eGFR in the same age group (Mann-Whitney U test). All data are expressed as the mean±standard deviation. BSA, body surface area; eGFR, estimated glomerular filtration rate.

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  Fig.2. Relationship of the age-adjusted CAVI with kidney function parameters in male and female participants. Bar charts of the age-adjusted CAVI stratified by the eGFR in (A) males and (B) females, and stratified by the BSA-adjusted eGFR in (C) males and (D) females were analyzed using a one-way ANOVA followed by Bonferroni multiple comparison test. ＊p＜0.001 versus the lowest stratified group (＜50 mL/min). All data are expressed as the mean±standard deviation. the CAVI, cardio-ankle vascular index; BSA, body surface area; eGFR, estimated glomerular filtration rate; ANOVA, analysis of variance.

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  Fig.3. Odds ratios for a high CAVI in tertiles of (A) eGFR and (B) the BSA-adjusted eGFR in male and female participants. Multivariate logistic regression analyses. Odds ratios (95% CIs) were calculated using T3 (upper tertile) as reference. FPG, SBP, LDL-C and triglycerides were included as covariates. the CAVI, cardio-ankle vascular index; eGFR, estimated glomerular filtration rate; BSA, body surface area; CI, confidence interval; FPG, fasting plasma glucose; SBP, systolic blood pressure; LDL-C, low-density lipoprotein cholesterol.