Role of Myocardial Strain Analysis by 2-Dimensional Speckle Tracking Echocardiography in Assessment of Severity of Coronary Artery Stenosis in Coronary Artery Disease Patients

Background: Myocardial strain analysis with 2D-speckle-tracking echocardiography, which is performed at resting position, offers valuable information about myocardial fiber changes in different types of myocardial diseases. Aim: This study evaluated the role of myocardial strain analysis in assessment of severity of coronary artery stenosis in coronary artery disease patients. Patients and methods: This study included 150 patients with suspected CAD, 50 patients were with Non-ST elevation ACS and 100 patients underwent stress ECG, 50 patients of them showed positive or equivocal stress ECG. patients were divided into two groups: Group A: 50 Patients with Non-ST elevation Acute coronary syndrome (NSTACS).and Group B: 50 Patients with positive or equivocal stress ECG. (Stable coronary artery disease). All patients underwent full history & examination, ECG, conventional & speckle tracking Echocardiography & both Gensini & Syntax scores were calculated for every patient. Results: The study revealed a significant lower GLPSS in Group A compared to Group B (p < 0.001). Also as regard the correlation of TLS and significant CAD lesion in each Coronary Artery Territories, a significant higher TLS correlated with significant lesion in LAD and LCX compared to non-significant lesions in Group A (P value= 0.001) While in Group B a significant higher TLS correlated with significant lesion in LAD, LCX and RCA compared to non-significant lesions (P value= 0.001) Conclusion: LVGLS and TLS have an incremental prognostic value and can be used to assess the severity of coronary stenosis in patients with coronary artery disease.