Why the study?
Does an abnormal diurnal blood pressure rhythm ('non-dipping') accelerate the decline of renal function in diabetic patients with hypertension and nephropathy?
Population
n=26 diabetic patients with hypertension, proteinuria and relentless progressive impairment of renal…
Comparison
Non-dipping blood pressure pattern vs Dipping blood pressure pattern
Design
Cohort
Follow-up
Between 1990 and 1996
Authors
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Non-dipping pattern associated with faster renal decline in diabetic nephropathy; leaves open whether restoring dipping slows progression.
Does an abnormal diurnal blood pressure rhythm ('non-dipping') accelerate the decline of renal function in diabetic patients with hypertension and nephropathy?
In diabetic patients with nephropathy, a 'non-dipping' blood pressure pattern is associated with a significantly faster decline in renal function compared to a normal diurnal rhythm.
Farmer et al. (1998) studied this question.
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