What does this research mean for the field?

Genetic variation accounts for a limited fraction of population differences in cardiometabolic disease, and addressing societally driven environmental determinants and socioeconomic barriers will have a markedly greater impact on reducing inequalities than pursuing genetic population stratifiers. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

April 26, 2024Trends in Molecular MedicineOpen Access

Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease

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Why the study?

Population differences in cardiometabolic disease remain unexplained, partly due to misleading assumptions over genetic explanations arising from terminology distinguishing populations.

Design

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Authors

SESophie V. EastwoodUCL Biomedical Research Centre GHGibran HemaniBristol City Council SWSarah WatkinsUniversity of Bristol

Discussion

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Implication

Supports prioritizing societal and environmental interventions for cardiometabolic equity; leaves open precise gene-environment contributions in future studies.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Eastwood et al. (2024) studied this question.

synapsesocial.com/papers/6a1996c63e4c9aaeb7f64600 https://doi.org/10.1016/j.molmed.2024.04.002

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Implication

Supports prioritizing societal and environmental interventions for cardiometabolic equity; leaves open precise gene-environment contributions in future studies.

Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider