What does this research mean for the field?

Q: What does this research mean for the field?

Treatment with atorvastatin improves small artery elasticity and reduces systolic and diastolic blood pressure in patients with severe hypercholesterolemia. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

November 1, 2001American Journal of HypertensionOpen Access

Treatment with atorvastatin improves small artery compliance in patients with severe hypercholesterolemia

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Why the study?

Does atorvastatin improve arterial compliance in patients with severe hypercholesterolemia?

Structured PICO

Does atorvastatin improve arterial compliance in patients with severe hypercholesterolemia?

Population

n=17 patients with severe hypercholesterolemia (LDL-C > 170 mg/dL), naive to hypolipidemic medication, without other risk factors or hypertension.

Intervention

Atorvastatin (dose not specified) for 20 weeks

Outcome

Arterial compliance (large and small artery elasticity index) at 20 weekssurrogate

Atorvastatin improves small artery elasticity and reduces blood pressure in patients with severe hypercholesterolemia without other risk factors.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support vascular benefits but should not change practice; leaves open causality and generalizability pending RCTs.

Cite This Study

Eyal Leibovitz (2001) studied this question.

synapsesocial.com/papers/6a199de71d4d911c80ea7159 https://doi.org/10.1016/s0895-7061(01)02210-5

Topics

PCSK9 inhibitors Statin therapy

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Treatment with atorvastatin improves small artery compliance in patients with severe hypercholesterolemia

Structured PICO

Discussion

Implication

Cite This Study

Topics

Treatment with atorvastatin improves small artery compliance in patients with severe hypercholesterolemia

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider