Key result
Combined systemic arterial compliance and aortic stiffness correctly identifies 100% of new CHD cases.
Why the study?
Proximal aortic compliance is lower in CHD patients compared with healthy controls, and non-invasive assessment may be useful as a risk marker for coronary disease.
Does non-invasive assessment of systemic arterial compliance and regional aortic stiffness discriminate newly-diagnosed CHD patients from matched controls?
Case-Control
Does non-invasive assessment of systemic arterial compliance and regional aortic stiffness discriminate newly-diagnosed CHD patients from matched controls?
Absolute Event Rate: 100% vs 87%
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Non-invasive assessment of arterial mechanical properties provides useful additional information for cardiovascular risk assessment, correctly identifying 100% of CHD cases when combining SAC and aortic stiffness.
Cameron et al. (1996) conducted a case-control in Coronary Heart Disease. Systemic arterial compliance and regional aortic stiffness vs. Matched controls was evaluated on Correct identification of cases and controls using both mechanical indices. Combined use of systemic arterial compliance and regional aortic stiffness correctly identified 100% of newly-diagnosed coronary heart disease cases and 87% of matched controls.
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