Why the study?
Does weight reduction improve symptoms in patients with extreme obesity and cardiopulmonary syndrome?
Does weight reduction improve symptoms in patients with extreme obesity and cardiopulmonary syndrome?
This early case series describes a reversible cardiopulmonary syndrome associated with extreme obesity (likely Obesity Hypoventilation Syndrome) and discusses the benefits of weight reduction.
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Weight reduction may relieve symptoms in extreme obesity with cardiopulmonary compromise; hypothesis-generating, requiring prospective validation.
A syndrome consisting of obesity, somnolence, cyanosis, periodic breathing, and polycythemia, with congestive heart failure has been observed in 6 patients. The effect of weight reduction and the mechanisms responsible for the symptoms and signs are discussed.
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Estes et al. (1957) studied this question.
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