What does this research mean for the field?

Gadolinium-enhanced MRI can elucidate the histologic characteristics of cardiac myxomas, with enhanced regions corresponding to viable tumor or inflammation and unenhanced regions reflecting necrosis or cystic changes, while cine MR images provide clearer morphologic depiction than spin-echo images. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate ECG-gated spin-echo and gadolinium-enhanced MR imaging for diagnosing atrial myxomas.

July 1, 1996Angiology

Morphologic and Histologic Characterization of Cardiac Myxomas by Magnetic Resonance Imaging

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Why the study?

Does MRI (SE, cine, and Gd-DTPA-enhanced) accurately characterize the morphology and histology of left atrial myxomas compared to extracted specimens?

Population

4 patients with left atrial myxoma

Comparison

Magnetic resonance imaging including ECG-gated… vs Histological examination of extracted specimens

Design

Case_series

Authors

HMHiroshi MatsuokaFujita Health University MHMareomi HamadaUwajima City Hospital THToshio HondaHoshi University

Discussion

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Implication

May aid myxoma characterization on MRI in select cases; leaves open need for prospective validation.

Key Points

The aim is to evaluate ECG-gated spin-echo and gadolinium-enhanced MR imaging for diagnosing atrial myxomas.
Imaged four patients with left atrial myxoma using a 1.5-T MR imager.
Obtained T1-weighted images and cine MR images before and after Gd-DTPA injection.
Histologically compared enhanced MR images with extracted tumor specimens.
Cine MR images depicted myxomas as low-intensity areas, while SE images showed them as high-intensity areas.
On post-Gd-DTPA images, two tumors were homogeneously enhanced and two were inhomogeneously enhanced.
The enhancement patterns corresponded with histologic findings, reflecting inflammation and necrosis.

Structured PICO

Does MRI (SE, cine, and Gd-DTPA-enhanced) accurately characterize the morphology and histology of left atrial myxomas compared to extracted specimens?

Population

4 patients with left atrial myxoma

Intervention

Magnetic resonance imaging (1.5-T) including ECG-gated spin-echo (SE), cine MR, and gadolinium-DTPA-enhanced MR

Comparator

Histological examination of extracted specimens

Outcome

Morphologic and histologic characterization of atrial myxomassurrogate

MRI, particularly combining cine and Gd-DTPA-enhanced sequences, provides clear morphological depiction and accurate histological characterization of cardiac myxomas.

Cite This Study

Matsuoka et al. (1996) studied this question.

synapsesocial.com/papers/6a19b7763f3ec013f0def7de https://doi.org/10.1177/000331979604700709

Topics

Cardiac MRI

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Morphologic and Histologic Characterization of Cardiac Myxomas by Magnetic Resonance Imaging

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Morphologic and Histologic Characterization of Cardiac Myxomas by Magnetic Resonance Imaging

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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