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December 9, 1997Proceedings of the National Academy of SciencesOpen Access

Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells

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Authors

RSRakesh SingalUniversity of MiamiRFRichard C. FerrisUniversity of MinnesotaJLJane A. LittleUniversity of North Carolina at Chapel Hill

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Singal et al. (1997) studied this question.

synapsesocial.com/papers/6a19b8ff3f3ec013f0defa33https://doi.org/10.1073/pnas.94.25.13724
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Expression of the Chicken β-Globin Gene Cluster in Mice: Correct Developmental Expression and Distributed Control1995 · 41 citations
  2. 2The developmental switch in embryonic ρ-globin expression is correlated with erythroid lineage-specific differences in transcription factor levels1992 · 55 citations
  3. 3DNA methylation and gene expression1991 · 710 citations
  4. 4Transcriptional regulation of hemoglobin switching in chicken embryos.1981 · 758 citations
  5. 5Tissue-specific DNA methylation in a cluster of rabbit beta-like globin genes.1980 · 173 citations