Key result
Advanced interatrial block increased the risk of incident atrial fibrillation (HR 1.63) and stroke or transient ischemic attack (HR 2.22) compared to normal P waves in the general population.
Why the study?
Is interatrial block associated with an increased risk of atrial fibrillation, stroke, or TIA in the general population?
Cohort (n=6,354)
Yes
Is interatrial block associated with an increased risk of atrial fibrillation, stroke, or TIA in the general population?
Interatrial block, particularly the advanced subtype, is a significant independent risk factor for atrial fibrillation, stroke, and TIA in the general population.
IAB is a rather frequent finding in the general population. IAB is a risk factor for AF and is associated with an increased risk of stroke or TIA independently of associated AF.Key messagesBoth partial and advanced interatrial block are associated with increased risk of atrial fibrillation in the general population.Advanced interatrial block is an independent risk factor for stroke and transient ischaemic attack.The clinical significance of interatrial block is dependent on the subtype classification.
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Istolahti et al. (2020) conducted a cohort in General population (n=6,354). Advanced interatrial block (aIAB) vs. Normal P waves was evaluated on Incident atrial fibrillation (HR 1.63, 95% CI 1.00-2.65, p=0.048). Advanced interatrial block increased the risk of incident atrial fibrillation (HR 1.63) and stroke or transient ischemic attack (HR 2.22) compared to normal P waves in the general population.
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