Key result
Interatrial block was significantly correlated with embolic stroke (r = 0.2; P<0.006), demonstrating a 61% prevalence among probable embolic stroke patients in sinus rhythm.
Why the study?
Is interatrial block associated with an increased risk of embolic stroke in neurological admissions?
Case-Control (n=293)
Is interatrial block associated with an increased risk of embolic stroke in neurological admissions?
Effect estimate: r = 0.2
p-value: p=< 0.006
Interatrial block is significantly correlated with embolic stroke, suggesting it may serve as a novel risk factor for embolic events.
May flag higher embolic stroke risk in sinus-rhythm patients; leaves open independent prediction and prospective validation.
BACKGROUND: Interatrial block (IAB; P wave > or = 110 ms) is highly prevalent and is strongly associated with atrial tachyarrhythmias and left atrial dysfunction, making it a potential embolic risk. METHODS AND RESULTS: Among 293 neurological admissions over 2 years, 85 patients were diagnosed with embolic strokes and 208 with nonembolic strokes. Patients were then matched for stroke risk factors and evaluated for IAB. Eighty-eight percent of probable embolic stroke patients showed sinus rhythm, demonstrating a 61% IAB prevalence. Only hypertension (P < 0.001; r = 0.3) and IAB (P < 0.006; r = 0.2) were significant and directly correlated. CONCLUSION: IAB could indeed be a novel risk for embolic strokes and further investigation is warranted.
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Ariyarajah et al. (2007) conducted a case-control in Embolic stroke (n=293). Interatrial block vs. Absence of interatrial block was evaluated on Embolic stroke (r = 0.2, p=< 0.006). Interatrial block was significantly correlated with embolic stroke (r = 0.2; P<0.006), demonstrating a 61% prevalence among probable embolic stroke patients in sinus rhythm.
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