Key Points
- The study aims to assess the incidence and clinical characteristics of mitral regurgitation in patients with coronary heart disease.
- Analyze 127 patients selected for coronary or left ventricular surgery based on symptom severity.
- Evaluate the presence of mitral regurgitation and its correlation with clinical signs such as murmurs and left ventricular measurements.
- Investigate the relationship between left ventricular ejection fraction and levels of mitral regurgitation.
- 39 out of 127 patients (31%) exhibited mitral regurgitation, commonly linked with antecedent myocardial infarction.
- A significant association was observed between increased severity of coronary arterial disease and mitral regurgitation (P<0.05).
- A decrease in left ventricular ejection fraction was correlated with higher rates of mitral regurgitation (P<0.001).
Structured PICO
PPopulation127 patients with coronary heart disease, selected with a view to coronary or left ventricular surgery on the basis of severity of symptoms
OOutcomeIncidence of mitral regurgitation and its clinical, electrocardiographic, and angiographic correlates
Mitral regurgitation is a common finding in severe coronary heart disease and is strongly associated with left ventricular dysfunction and elevated filling pressures, though clinical murmurs are often absent.