What question did this study set out to answer?

To assess whether patients with psoriasis have more severe and difficult-to-manage hypertension compared to hypertensive patients without psoriasis.

March 29, 2011PLoS ONEOpen Access

Psoriasis and Hypertension Severity: Results from a Case-Control Study

View Full Paper

Ask AI

Bookmark

Authors

AAApril W. ArmstrongUniversity of Southern California SLSteven W. LinUniversity of Minnesota Medical Center CCCynthia J. ChambersCalifornia Northstate University

Discussion

Member takes

Implication

Case-control study reveals greater hypertension severity in psoriasis patients, indicating difficult blood pressure management linked to systemic inflammation.

Key Points

To assess whether patients with psoriasis have more severe and difficult-to-manage hypertension compared to hypertensive patients without psoriasis.
Conducted an electronic medical record case-control study matching 835 hypertensive patients with psoriasis to 2,418 hypertensive controls without psoriasis based on age, sex, and body mass index.
Assessed hypertension severity by the number of concurrent antihypertensive medication classes required.
Performed univariate and multivariable analyses adjusting for diabetes, hyperlipidemia, and race.
Treatment with multiple antihypertensives showed a significant independent association with psoriasis in multivariable analysis (p < 0.0001).
Psoriasis patients had increased odds of requiring monotherapy (OR 5.0, 95% CI 3.60–7.05), dual therapy (OR 9.5, 95% CI 6.68–13.65), triple therapy (OR 16.5, 95% CI 11.01–24.84), and quadruple or centrally-acting therapy (OR 19.9, 95% CI 10.58–37.33) relative to controls.

Cite This Study

Armstrong et al. (2011) studied this question.

synapsesocial.com/papers/6a19ecfda2165c1276df3622 https://doi.org/10.1371/journal.pone.0018227

View Full Paper

Ask AI

Bookmark

Implication

Case-control study reveals greater hypertension severity in psoriasis patients, indicating difficult blood pressure management linked to systemic inflammation.

Psoriasis and Hypertension Severity: Results from a Case-Control Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Psoriasis and Hypertension Severity: Results from a Case-Control Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider