What does this research mean for the field?

Most coronary vascular capacitance resides in the small intramural vessels, and accurate modeling of coronary flow patterns requires accounting for both small vessel capacitance and vascular waterfall effects. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1984Circulation Research

The role of vascular capacitance in the coronary arteries.

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Population

Experimental model of left coronary artery perfusion (hearts)

Design

Preclinical

Authors

JLJ LeeRJ Lee Group (United States)DCDavid ChambersCenters for Disease Control and Prevention SASatoshi AkizukiKawasaki Municipal Hospital

Discussion

Member takes

Implication

Preclinical capacitance and tone-dependent closing pressure values leave open translation to human coronary physiology; clinical studies required.

Structured PICO

Population

Experimental model of left coronary artery perfusion (hearts)

Intervention

Nonpulsatile pressure perfusion and analysis of transients

Outcome

Coronary capacitance and critical closing pressuresurrogate

This preclinical study demonstrates that most coronary capacitance resides in small intramural vessels and that critical closing pressure is tone-dependent.

Cite This Study

Lee et al. (1984) studied this question.

synapsesocial.com/papers/6a1a2ab39dd58c84b95b5ebb https://doi.org/10.1161/01.res.55.6.751

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Implication

Preclinical capacitance and tone-dependent closing pressure values leave open translation to human coronary physiology; clinical studies required.

The role of vascular capacitance in the coronary arteries.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The role of vascular capacitance in the coronary arteries.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider