Key result
Active-fixation leads had a 0.8% incidence of clinically relevant cardiac perforation; predictors included age >80 years (OR 3.84), female sex (OR 3.14), and apical RV lead position (OR 3.37).
Why the study?
What is the incidence and what are the predictors of clinically relevant cardiac perforation associated with active-fixation pacing and defibrillation leads?
Observational (n=2,200)
No
What is the incidence and what are the predictors of clinically relevant cardiac perforation associated with active-fixation pacing and defibrillation leads?
Active-fixation pacing and defibrillation leads have a low 0.8% incidence of clinically relevant cardiac perforation, though risk is significantly increased in females, patients over 80 years old, and with apical right ventricular lead positioning.
No takes yet. Share an insight, caveat, or question.
Supports heightened vigilance in elderly females and apical RV positioning; leaves open prospective validation of predictors.
Cano et al. (2016) conducted an observational in Active-fixation pacing and defibrillation lead implantation (n=2,200). Active-fixation pacing and defibrillation leads was evaluated on clinically relevant cardiac perforation. Active-fixation leads had a 0.8% incidence of clinically relevant cardiac perforation; predictors included age >80 years (OR 3.84), female sex (OR 3.14), and apical RV lead position (OR 3.37).
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