Prognosis of patients with left ventricular dysfunction, with and without viable myocardium after myocardial infarction. Relative efficacy of medical therapy and revascularization.
Why the study?
Does myocardial revascularization reduce ischemic events and cardiac death in patients with left ventricular dysfunction and viable myocardium after myocardial infarction compared to medical therapy?
Population
129 patients with left ventricular dysfunction and resting perfusion defects after myocardial infarction who…
Comparison
Myocardial revascularization vs Medical therapy
Design
Cohort
Follow-up
17 +/- 9 months
Authors
Discussion
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Member takes
Implication
Revascularization was associated with fewer ischemic events in FDG+ viable myocardium; extends observational viability data but leaves randomized confirmation open.
Structured PICO
Does myocardial revascularization reduce ischemic events and cardiac death in patients with left ventricular dysfunction and viable myocardium after myocardial infarction compared to medical therapy?
P
Population
129 patients with left ventricular dysfunction and resting perfusion defects after myocardial infarction who underwent positron emission tomography with both dipyridamole stress Rb-82 perfusion imaging and FDG imaging.
I
Intervention
Myocardial revascularization
C
Comparator
Medical therapy
O
Outcome
Nonfatal ischemic events and cardiac deathhard clinical
In patients with left ventricular dysfunction after myocardial infarction, residual viable myocardium is associated with a high risk of ischemic events that is significantly attenuated by revascularization.
Cite This Study
Lee et al. (1994) studied this question.