Why the study?
It remained unclear whether different blood pressure management strategies should be administered for acute stroke patients with or without impaired renal function.
Does early antihypertensive treatment reduce the composite outcome of death and major disability in acute ischemic stroke patients with different renal function status?
Does early antihypertensive treatment reduce the composite outcome of death and major disability in acute ischemic stroke patients with different renal function status?
Early antihypertensive treatment during hospitalization has a neutral effect on clinical outcomes in acute ischemic stroke patients, regardless of baseline renal function.
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No benefit from early antihypertensives on death or major disability across renal strata in acute ischemic stroke; confirms neutral effect without interaction.
Zhai et al. (2022) studied this question.
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