Why the study?
Does aortic valve morphology influence regurgitant volume in an in vitro model of aortic regurgitation?
Population
Four aortic valve templates modelled after circular, rheumatic, degenerative, and bicuspid lesions, with…
Comparison
Bicuspid and degenerative valve shapes vs Circular or rheumatic valve shapes
Design
Preclinical
Authors
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Experimental data suggest valve morphology affects AR regurgitant volume; leaves open impact on clinical grading or modeling.
Does aortic valve morphology influence regurgitant volume in an in vitro model of aortic regurgitation?
In an in vitro model, degenerative and bicuspid aortic valve shapes allowed significantly more regurgitant flow than rheumatic or circular orifices due to a higher contraction coefficient.
Grayburn et al. (1991) studied this question.
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