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February 1, 1998Journal of Biological ChemistryOpen Access

The Shp-2 Tyrosine Phosphatase Has Opposite Effects in Mediating the Activation of Extracellular Signal-regulated and c-Jun NH2-terminal Mitogen-activated Protein Kinases

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Authors

ZSZhongqing ShiNanjing Drum Tower HospitalWLWei LüJiangnan UniversityGFGen‐Sheng FengUniversity of California, San Diego

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Cite This Study

Shi et al. (1998) studied this question.

synapsesocial.com/papers/6a1a3893208efea2cbef195chttps://doi.org/10.1074/jbc.273.9.4904
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1SH2 Domains of the p85α Subunit of Phosphatidylinositol 3-Kinase Regulate Binding to Growth Factor Receptors1992 · 185 citations
  2. 2A Deletion Mutation in the SH2-N Domain of Shp-2 Severely Suppresses Hematopoietic Cell Development1997 · 167 citations
  3. 3A Novel Membrane Glycoprotein, SHPS-1, That Binds the SH2-Domain-Containing Protein Tyrosine Phosphatase SHP-2 in Response to Mitogens and Cell Adhesion1996 · 456 citations