This study demonstrates a high prevalence of metabolic syndrome (49.8%) among Northern Plains and Southwest American Indians, highlighting a significant cardiovascular risk in this population.
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Signals substantial CV risk in American Indians; leaves open whether targeted prevention improves outcomes.
OBJECTIVE: To estimate the prevalence of metabolic syndrome by age, sex, and diabetes status in Northern Plains and Southwest American Indians. RESEARCH DESIGN AND METHODS: Data for this analysis came from the Education and Research Toward Health (EARTH) study, a 5-year cross-sectional study of Southwest and Northern Plains American Indian adults. The National Cholesterol Education Program's Adult Treatment Panel III (NCEP/ATP III) guidelines were used to identify adults with metabolic syndrome. RESULTS: The age-adjusted prevalence of the metabolic syndrome was 49.8% among 4,457 participants aged 18-88 years. Age-adjusted prevalence was 42.4% for participants without diabetes and 86.6% for participants with diabetes. In participants aged <40 years, the overall prevalence of metabolic syndrome was 53.1%; 44.9% after excluding individuals with diabetes. CONCLUSIONS: This study confirms a high prevalence of the metabolic syndrome among Northern Plains and Southwest American Indians of all ages.
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Sinclair et al. (2010) studied this question.
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