Why the study?
Ischemic heart disease has significantly increased in women, and the prognostic value of fasting glycemia in female ACS patients required evaluation.
Does elevated fasting glycemia on admission predict death and complications in non-diabetic women with acute coronary syndrome?
Does elevated fasting glycemia on admission predict death and complications in non-diabetic women with acute coronary syndrome?
Elevated baseline fasting glycemia on admission in female patients diagnosed with ACS is a predictor of risk of death and complications during the hospital phase.
Hypothesis-generating for admission glycemia in non-diabetic women with ACS; prospective validation required before clinical use.
Ischemic heart disease is one of the leading causes of death in the world and in Cuba, with a significant increase in women. An observational, descriptive, cross-sectional study was carried out with the aim of evaluating the prognostic value of fasting glycemia determined in the first 24 hours of admission in women with a diagnosis of acute coronary syndrome (ACS) hospitalized in the coronary service of the Carlos J. Finlay HMC during 2015-2017. The universe consisted of 250 women over 20 years of age with a diagnosis of ACS and the sample consisted of 224 patients. Two groups were formed to compare each other: study group (≥6.11 mmol/L) with high fasting glucose value and control group (<6.11 mmol/L) with normal value. The mean glycemia value was higher in the study group being statistically significant (p < 0.000001). Age did not show significant difference between groups. HT (p<0.007), smoking (p<0.05) and ACS (p<0.004) in any of their clinical variants were statistically significant variables. Death as a complication was present in only 15 patients in the study group, representing 24.1% of deaths. There were no significant statistical differences in terms of coronary angiography results, since not all patients with ACS presented indications for this study. Conclusions: The results of the study suggest that an elevated baseline fasting glycemia on admission in female patients diagnosed with ACS is a predictor of risk of death and complications during the hospital phase.
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Osorio-González et al. (2023) studied this question.
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