The alternative splicing of the CD45 tyrosine phosphatase is controlled by negative regulatory trans-acting splicing factors.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The role of the mammalian branchpoint sequence in pre-mRNA splicing.1988 · 214 citations
2. 2Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains dfffering in the number of internal repeats1984 · 219 citations
3. 3Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene.1991 · 186 citations
4. 4Transitions from high to low molecular weight isoforms of CD45 (T200) involve rapid activation of alternate mRNA splicing and slow turnover of surface CD45R.1989 · 70 citations
5. 5Complete exon-intron organization of the human leukocyte common antigen (CD45) gene.1988 · 106 citations