Why the study?
Does rate-adapted ventricular pacing or dual chamber pacing improve cardiac output compared to fixed-rate ventricular pacing in patients with DDD pacemakers?
Does rate-adapted ventricular pacing or dual chamber pacing improve cardiac output compared to fixed-rate ventricular pacing in patients with DDD pacemakers?
In patients with pacemakers, increasing the heart rate during exercise is the major determinant of improved cardiac output, while at rest, AV synchrony is superior for ventricular filling.
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AV synchrony at rest and rate adaptation during exercise may optimize cardiac output in pacemaker patients; leaves open effects on symptoms or survival in current practice.
McMeekin et al. (1990) studied this question.
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