Why the study?
Does 36 hours of total sleep deprivation alter cardiovascular autonomic modulation in normal humans?
Population
18 normal subjects (16 men, 2 women, mean age 26.0 +/- 4.6 years)
Comparison
36 hours of total sleep deprivation vs Baseline measurements prior to sleep deprivation
Design
Cohort
Follow-up
36 hours
Authors
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Acute sleep deprivation may impair autonomic balance in healthy adults; hypothesis-generating for links to cardiovascular risk.
Does 36 hours of total sleep deprivation alter cardiovascular autonomic modulation in normal humans?
Acute sleep deprivation shifts cardiovascular autonomic balance toward increased sympathetic and decreased parasympathetic tone, which may contribute to adverse cardiovascular effects.
Zhong et al. (2005) studied this question.
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