Why the study?
Does spaceflight-induced orthostatic intolerance relate to subnormal norepinephrine release in astronauts?
Population
40 astronauts before and after spaceflights lasting up to 16 days
Comparison
Upright posture testing after spaceflight vs Upright posture testing before spaceflight, and…
Design
Cohort
Follow-up
up to 16 days
Authors
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Postflight orthostatic intolerance was associated with blunted norepinephrine response; hypothesis-generating for autonomic dysfunction mechanisms in terrestrial patients.
Does spaceflight-induced orthostatic intolerance relate to subnormal norepinephrine release in astronauts?
Postflight orthostatic intolerance in astronauts is associated with hypoadrenergic responsiveness, which may also provide insights into autonomic dysfunction in Earthbound patients.
Fritsch-Yelle et al. (1996) studied this question.
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