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Case report demonstrates the diagnosis of a large apocrine tumor in a woman, highlighting its management and implications.
Large subcutaneous masses are relatively uncommon and usually benign. Lipomatous tumors predominate and are typically nonmalignant; however, atypical lipomatous tumors and liposarcomas can occur. Although malignancy is uncommon overall, soft tissue sarcomas may present as large or deep subcutaneous masses. A woman in her 50s presented to the primary care clinic with a large, firm, and mobile mass on the posterior aspect of the left shoulder that had been present for seven years. After excisional biopsy, pathological evaluation confirmed the diagnosis of cutaneous mixed tumor, apocrine type (chondroid syringoma). Cutaneous mixed tumor is a rare and typically benign neoplasm that can arise from either eccrine or apocrine glands and typically presents as a slow-growing, painless nodule. Definitive management and treatment involve surgical excision with a goal of removal of the entire tumor to avoid both recurrence and rare instances of malignant transformation.
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Bernstein et al. (2026) studied this question.
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