Goldilocks boronic esters: optimized properties through understanding hydrolysis kinetics

Reyner D. Vargas; Samantha Setsuko Cox; James O. Larkin; Jingfei Dai; Yuecheng Jiang; Ivan Yuan; Margaret Hankins; Zachary Thomas Ball

doi:10.1039/d6sc01941b

January 1, 2026Chemical ScienceOpen Access

Goldilocks boronic esters: optimized properties through understanding hydrolysis kinetics

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to optimize the properties of boronic esters by understanding their hydrolysis kinetics.
Investigated the reversible reaction between boronic acids and diols to form boronic esters.
Analyzed hydrolysis kinetics to evaluate the stability of boronic esters as protecting groups in synthesis.
Demonstrated that specific hydrolysis rates influence the stability and utility of boronic esters in multistep synthesis.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Optimized properties of boronic esters through understanding hydrolysis kinetics, indicating potential applications in synthesis.

Abstract

Boronic acids react reversibly with diols to form boronic ester derivatives, a process that can be used as a protecting group in multistep synthesis. But boronic ester formation is also...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Vargas et al. (2026) studied this question.

synapsesocial.com/papers/6a1a82640307b78509434154 https://doi.org/10.1039/d6sc01941b

View Full Paper

Ask AI

Bookmark

Share

Goldilocks boronic esters: optimized properties through understanding hydrolysis kinetics

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Goldilocks boronic esters: optimized properties through understanding hydrolysis kinetics

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading