⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

May 28, 2026Regional Anesthesia & Pain Medicine

In reply: methodological arguments against evidence synthesis of implantable peripheral nerve stimulation for chronic pain

Ryan D’Souza Nasir Hussain

View at Publisher

Ask AI

Bookmark

Share

Key Points

This response aims to discuss methodological concerns related to the synthesis of evidence on implantable peripheral nerve stimulation for chronic pain.
Analyzed insights provided by Hakim and Narouze regarding their perspectives on the systematic review.
Evaluated challenges associated with conducting systematic reviews and meta-analyses.
Identified several methodological arguments against the evidence synthesis presented in the systematic review.
Highlighted the complexity and challenges that arise in systematic reviews and meta-analyses.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Implication

Reply addresses methodological challenges in synthesizing evidence on implantable peripheral nerve stimulation for chronic pain.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

D’Souza et al. (2026) studied this question.

synapsesocial.com/papers/6a1a82b80307b7850943461b https://doi.org/10.1136/rapm-2026-108032

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Implantable peripheral nerve stimulation for chronic pain: a systematic review and meta-analysis of analgesic outcomes up to 24 monthsMeta-Analysis · 2025 · 14 citations
2Methodological limitations and conflicts of interest in spinal cord stimulation research impair trustworthinessMeta-Analysis · 2026
3Effects of neuromodulation techniques on neuropathic pain: a systematic review and network meta-analysisMeta-Analysis · 2026
4Long-term efficacy of neuromodulation in chronic pain management: a single-center retrospective studyCohort Study · 2026
5Peripheral Nerve Stimulation Uses High-Frequency Electromagnetic Coupling Technology to Power an Implanted Neurostimulator With a Separate Receiver for the Treatment of Chronic Knee Pain: A Retrospective Study2024

Neuromodulation for chronic pain2021
Combined spinal cord and peripheral nerve stimulation in severe neuropathic pain syndrome2025
Peripheral Nerve Stimulation Uses High-Frequency Electromagnetic Technology to Power an Implanted Neurostimulator with a Separate Receiver for the Treatment of Chronic Pain in the Lower Extremities2024
Prevalence and intensity of chronic postsurgical pain after cranial surgery: a systematic review and meta-analysis of randomized and non-randomized studiesRegional Anesthesia & Pain Medicine · 2026
Reporting of commercial involvement and the direction of stated conclusions in the neuromodulation-for-pain literature: a meta-research study of 896 publicationsRegional Anesthesia & Pain Medicine · 2026

More from Regional Anesthesia & Pain Medicine

More from Mayo Clinic

More from The Ohio State University Wexner Medical Center