Why the study?
Current imaging guidelines do not include stress echocardiography as a recommended tool for evaluating patients when microvascular dysfunction causes symptoms without identifiable epicardial luminal stenosis.
Is stress echocardiography useful in diagnosing myocardial ischemia due to microvascular dysfunction in nonobstructive coronary artery disease?
Is stress echocardiography useful in diagnosing myocardial ischemia due to microvascular dysfunction in nonobstructive coronary artery disease?
Stress echocardiography may be a useful imaging modality for identifying microvascular dysfunction in patients with nonobstructive coronary artery disease, despite not being currently recommended by guidelines for this specific indication.
Should not yet alter diagnostic algorithms for nonobstructive CAD; hypothesis-generating for stress echocardiography in microvascular dysfunction.
Identification of ischemia remains critical when assessing individuals presenting with atypical symptoms or in patients with known coronary artery disease (CAD). Several imaging modalities are currently available to attain this diagnostic goal. Unfortunately, not all case presentations are straightforward, particularly when microvascular dysfunction (MVD) is the cause of symptoms in the absence of identifiable epicardial luminal stenosis. Specifically, in such cases, current imaging guidelines do not include stress echocardiography (SE) as a recommended tool when assessing these patients. We present three cases that highlight the utility of SE for identifying MVD and provide mechanistic explanations. We believe that SE should not be completely discarded as an inadequate testing modality; we highlight the potential utility of this imaging modality not only in diagnosing CAD and pre-surgical evaluation of patients but also in identifying patients with MVD.
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Baweja et al. (2021) studied this question.
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