What does this research mean for the field?

In the first two months following acute myocardial infarction, transient myocardial ischemia becomes increasingly common, is predominantly silent, and is more closely associated with increased myocardial oxygen demand during late compared to early recovery. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To determine the prevalence and clinical characteristics of transient myocardial ischaemia during both early and late recovery phases after acute myocardial infarction.

November 1, 1990HeartOpen Access

Transient myocardial ischaemia after acute myocardial infarction.

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Why the study?

What is the prevalence and characteristics of transient myocardial ischemia early versus late after acute myocardial infarction?

Population

203 patients with recent acute myocardial infarction

Design

Cohort

Follow-up

38 days

Authors

PCPeter D. CurrieAustralian Regenerative Medicine Institute SSS SaltissiDeakin University

Discussion

Member takes

Implication

May warrant extended monitoring for silent ischemia post-MI; leaves open whether detection alters outcomes or management.

Key Points

To determine the prevalence and clinical characteristics of transient myocardial ischaemia during both early and late recovery phases after acute myocardial infarction.
Prospective study of 203 patients with recent acute myocardial infarction.
Continuous ambulatory ST-segment monitoring conducted at early (mean 6.4 days) and late (mean 38 days) post-infarction intervals.
Transient ST-segment depression was observed in 32% of patients during late monitoring compared to 14% during early monitoring.
Greater than 85% of all ischaemic episodes were clinically silent, and 80% of affected patients experienced silent ischaemia exclusively.
Late ischaemic events exhibited a diurnal pattern, began at higher resting heart rates, and were accompanied by greater heart rate increases than early events.

Structured PICO

What is the prevalence and characteristics of transient myocardial ischemia early versus late after acute myocardial infarction?

Population

203 patients with recent acute myocardial infarction

Intervention

Ambulatory monitoring of the ST segment at early (6.4 days) and late (38 days) timepoints

Outcome

Prevalence and characteristics of transient myocardial ischaemia (ST segment depression)surrogate

Transient myocardial ischemia becomes more common and more closely associated with increased myocardial oxygen demand in the first 2 months after acute myocardial infarction, with most episodes being clinically silent.

Cite This Study

Currie et al. (1990) studied this question.

synapsesocial.com/papers/6a1a8edd7ff99bba0645dbfa https://doi.org/10.1136/hrt.64.5.299

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Transient myocardial ischaemia after acute myocardial infarction.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Transient myocardial ischaemia after acute myocardial infarction.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider