What does this research mean for the field?

The coordinated assembly of dihydropyridine receptors (DHPRs) and ryanodine receptors (RyRs) during muscle development establishes the precise structural relationship required for excitation-contraction coupling in skeletal and cardiac muscle. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 23, 1996Proceedings of the National Academy of SciencesOpen Access

Formation of junctions involved in excitation-contraction coupling in skeletal and cardiac muscle.

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Structured PICO

Population

Skeletal and cardiac muscle (basic science review)

This review provides a model for the assembly of intracellular junctions and the structural relationship between DHPRs and RyRs in skeletal and cardiac muscle excitation-contraction coupling.

Discussion

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Implication

Hypothesis-generating model of DHPR-RyR junctions in EC coupling; leaves open experimental validation before any clinical consideration.

Cite This Study

Flucher et al. (1996) studied this question.

synapsesocial.com/papers/6a1a8f7fe916fa6dd3b8bdb3 https://doi.org/10.1073/pnas.93.15.8101

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Formation of junctions involved in excitation-contraction coupling in skeletal and cardiac muscle.

Structured PICO

Discussion

Implication

Cite This Study

Formation of junctions involved in excitation-contraction coupling in skeletal and cardiac muscle.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

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